NeoFipronis^® (Pronidesivir) Treatment Guide

For cats diagnosed with feline infectious peritonitis (FIP), including effusive (wet), non-effusive (dry), neurological, and ocular forms.

Standard Dosage

• 15mg/kg/day — equivalent to half a 30mg tablet per kg of body weight.
• Administer on an empty stomach (1 hour before or 2 hours after food).
• Once daily, preferably at the same time each day.

Increased Dosage (Under Veterinary Supervision Only)

Important Notes

• Do not alter the dosage or frequency without veterinary guidance.
• Avoid missed, incorrect, or duplicate doses.
• Continue monitoring for at least 8 weeks after stopping treatment to detect any signs of relapse.

The treatment course should last no less than 84 days (12 weeks), with an additional 2 weeks of consolidation after symptom resolution.

• Accurate dosing by weight: The standard dose is 15mg/kg once daily (i.e., half a 30mg tablet per kg of body weight). Higher doses (up to 30mg/kg) may be required for neurological or ocular FIP—only adjust under veterinary guidance.
• Administer once daily only: Do not split the dose or give more than once a day. Overdosing may lead to increased risk of side effects.
• Give on an empty stomach: Administer 1 hour before or 2 hours after meals to optimize absorption and bioavailability.
• Avoid missed or double doses: Skipping or doubling doses may reduce treatment efficacy or increase the risk of adverse effects.
• Never adjust the dose without vet advice: Even if symptoms improve or worsen, do not change the dosage on your own.
• Stick to a consistent schedule: Giving the medication at the same time each day helps maintain stable blood concentration for optimal results.
• Complete the full treatment course: Continue for at least 12 weeks even if symptoms resolve early to prevent relapse or resistance.

Administration

• Dosage: 15mg/kg once daily (½ tablet per kg); increase to 30mg/kg for neurological or ocular FIP under veterinary supervision.
• Timing: Administer once daily on an empty stomach (1 hour before or 2 hours after food).
• Consistency: Give at the same time each day to maintain stable blood levels.

Precautions

• Do not skip, double, or adjust doses without veterinary direction.
• Monitor your cat’s appetite, energy levels, and temperature throughout treatment.
• Regular blood tests (liver, kidney function) are recommended.
• Ensure proper nutrition, hydration, and a low-stress environment.

Complete the full course (≥84 days), then continue 2 weeks for consolidation, and observe for 8 weeks post-treatment to detect relapse.

Minimum Duration

• Minimum duration: 12 weeks (84 days)
• Continue treatment for 2 additional weeks after full symptom resolution
• Monitor for 8 weeks post-treatment to check for relapse
• In severe cases or slow recovery, treatment may be extended to 15–16 weeks

Complete the full treatment course—at least 12 weeks—with 2 extra weeks after symptoms resolve, and monitor closely for 8 weeks post-treatment to prevent relapse. Severe cases may need extended therapy.