Introduction
Feline Infectious Peritonitis (FIP) is a severe disease caused by mutations of the feline coronavirus. For decades, it was regarded as incurable, but with the introduction of antiviral drugs such as GS-441524 and its veterinary formulations like Pronidesivir (NeoFipronis®), both prevention and treatment strategies for FIP have advanced significantly. This article provides cat owners and veterinarians with essential knowledge about how to reduce the risk of FIP and how to treat it effectively when diagnosed.
1. Understanding the Risk and Cause of FIP
FIP develops when the commonly found feline coronavirus (FCoV) mutates inside a cat’s body. While most cats infected with FCoV show mild or no symptoms, in some cases the mutated virus spreads through immune cells, triggering severe inflammation that damages vital organs.
2. How to Prevent FIP
There is no fully effective vaccine against FIP, so prevention relies on management and hygiene
Keep litter boxes clean and separate in multi-cat households
Reduce overcrowding and environmental stress to support immunity
Practice responsible breeding and cattery management to lower viral spread
Ensure proper nutrition and regular veterinary checkups to maintain overall health
3. Correct Treatment Options for FIP
FIP is no longer untreatable, thanks to antiviral therapies
GS-441524 and Pronidesivir (NeoFipronis®) are the most effective options, directly blocking viral replication with survival rates above 80–90%
Standard treatment lasts around 12 weeks (84 days), with dosage adjusted by weight and severity. Neurological and ocular cases require higher doses
Supportive care includes proper nutrition, fluid therapy, supplements such as taurine and omega-3s, and medications for anemia or secondary infections if needed
4. Recovery and Long-Term Outlook
Most cats treated with the correct regimen achieve full recovery and return to normal lives. Relapse may occur if treatment is stopped early or doses are insufficient, so completing the full course and regular monitoring are essential.
Conclusion
FIP is no longer a hopeless condition. With early diagnosis, strict treatment compliance, and modern antivirals like NeoFipronis® (Pronidesivir), cats can now recover and live healthy lives. Prevention through good management and timely medical care remains equally important to reduce risks in multi-cat environments.